There is no one definitive answer to this question. However, there are a few things to keep in mind when deciding when is the best time to send out a newsletter.
First, consider the purpose of your newsletter. If it is designed to communicate new updates or changes to your company, then it may be better to send it out at the beginning of the week.
This will give your subscribers enough time to digest the information before the weekend arrives.
Second, consider the size of your audience. If you have a small audience, it may be better to send out your newsletter on a weekday rather than on a weekend.
This will ensure that your subscribers have more time to read it before the week ends.
Finally, consider how often you plan on sending out your newsletter. If you plan on sending it out once per month, then it may be best to send it out on a weekday rather than on a weekend.
This will give your subscribers more time to read and respond to the content before the month ends.